Jamieson Health Center


April 14, 2011

Volume 3, Number 3


Dear patients, dear friends,


Leaky Gut is a very serious condition that can lead to chronic conditions such as autoimmune and neurological disorders. It can cause chronic pain, depression, chronic fatigue, brain fog and even obesity and cardiovascular diseases. It can be, but is not always, accompanied by intestinal issues and food intolerances, which can cause multiple food sensitivities, irritable bowel syndrome, celiac disease, and chronic yeast overgrowth.


Leaky gut seems to be a term with which many of you are familiar. But I dont think everyone understands the complexity of Leaky Gut, what causes it and how it can be helped. Ive had patients tell me that they or their child have leaky gut, yet they continue to eat the very foods that cause leaky gut.


Leaky gut develops when tight junctions in the intestinal mucosa are compromised and allow large, undigested compounds from the foods you eat, toxins and/or bacteria to pass through the intestinal wall. This creates additional immune responses and a vicious cycle of intestinal inflammation and greater loss of intestinal permeability. This vicious cycle leads to autoimmunity in the intestines as well as to other organs such as skeletal muscle, pancreas, kidney, liver and the brain, resulting in neuro-autoimmunity.


There are several factors that contribute to Leaky Gut. They are:


        Neurological issues and brain degeneration

        Physical, chemical and emotional stress

        Low hormone levels

        Metabolic issues such as autoimmunity

        Intestinal infections

        Medications such as antibiotics


The more factors that apply to you, the higher your risk for Leaky Gut, which translates to a higher risk for chronic disorders.


Many patients think: Its easy to heal my intestines, I just need to take enough glutamine. Unfortunately, healing from Leaky Gut is much more complex and means addressing each one of the above factors:


  As a first step, I suggest a leaky gut blood panel to establish a base line and to encourage you to stay compliant with treatments, diet and lifestyle changes.


  Dietary causes need to be addressed with a customized intestinal repair program including dietary changes and specific nutritional support optimized to help you break the vicious cycle of leaky gut.


  It is absolutely necessary to avoid all fast and processed foods, sugar, alcohol, and especially any foods containing gluten and casein. For a complete list of which foods to eat and to avoid, read the section below.


  Gluten sensitivity equals leaky gut. That means when you are gluten sensitive, you have a leaky gut. You need to cut all grains from your diet. To learn more about gluten sensitivity and cross-reactive foods, please read our February 2011 newsletter.


  Using my integrative approach, I can also help identify and eliminate any physical, chemical and emotional stressors exacerbating leaky gut.


  Since there is a direct connection between the brain and the gut, it is important to keep your brain at optimal health. Chiropractic adjustments and Advanced Neurofeedback training can help stimulate and optimize your brain function.


  Metabolic issues, infections and hormonal deficiencies cause leaky gut. I can help you manage your autoimmune disorders, balance hormones, curtail infections such as H. Pylori, bacterial and yeast overgrowth, and eliminate parasitic infections with clinically proven supplements.


If you are suffering from a chronic condition including depression, I suggest you get checked for leaky gut. If you test positive, you should feel encouraged and empowered because you will know exactly what to do to help improve and heal from your condition.


I want to let you know that there is hope for your chronic condition!


Yours in good health,

Dr. Samuel Jamieson, D.C.


Is Leaky Gut causing your chronic issues?



What is Leaky Gut Syndrome?

Leaky Gut is a real syndrome. It is caused by compromised intestinal permeability. When tight junctions of the intestinal mucosa are compromised, they become widened and permeable to large, undigested compounds from the foods you eat, toxins and bacteria.


The underlying intestinal immune system reacts against the large compounds of absorbed yet undigested proteins. This reaction then promotes exaggerated immune responsiveness, which causes food sensitivities. This in turn creates a viscous cycle of further intestinal inflammation and greater loss of intestinal permeability.


Leaky Gut is a serious condition leading to autoimmune and neurological disorders.

Unfortunately, Leaky Gut is not just a disorder of the intestines. Yes, some patients complain about multiple food sensitivities, allergies and food intolerances. The scary part of leaky gut is that once the vicious cycle of inflammation in the intestines has started, the immune system creates antibodies against the intestinal tissue leading to intestinal autoimmunity. It also creates antibodies against the dietary proteins, which causes cross-reactions with other tissues in the body and induces autoimmune diseases in other organs such as skeletal muscle, pancreas, kidney, liver, brain, etc. At this point, the blood brain barrier is also compromised which further increases the risk for nervous system abnormalities.


Recent studies show that there exists a gut-brain connection in patients with major depression. I quote:

The results show that intestinal mucosal dysfunction, characterized by an increased translocation of gram-negative bacteria known as leaky gut, plays a role in the inflammatory pathophysiology of depression. It is suggested that patients with major depression should be checked for leaky gut and, accordingly, should be treated for leaky gut.

(Neuro Endocrinol Lett. 2008 Jun;29(3):287-91)


More specific, as studies show, Leaky Gut creates a spectrum of patients with the following conditions:


  Autoimmune disorders (Nat Clin Pract Gastroenterol Hepatol. 2005 Sep;2(9):416-22)

  Celiac disease (Ann N Y Acad Sci. 2009 May;1165:195-205)

  Type 1 diabetes (Diabetes. 2008 Oct;57(10):2555-62; Diabetologia. 2006 Dec; 49 (12): 2824-7. Epub 2006 Oct. 7)

  Chronic Fatigue Syndrome (Neuro Endocrinol Lett. 2008 Dec;29(6):902-10; Neuro Endocrinol Lett. 2008 Jun;29(3):313-9)

  Chronic Inflammatory Conditions (Clin Rev Allergy Immunol. 2009 Feb;36(1):40-51)

  Cardiovascular conditions leading to chronic heart failure (Curr Opin Clin Nutr Metab Care. 2008 Sep;11(5):632-9; Eur Heart J. 2005 Nov;26(22):2368-74)

  Obesity (Acta Gastroenterol Belg. 2010 Apr-Jun;73(2):267-9)

  Chronic depression (Neuro Endocrinol Lett. 2008 Jun;29(3):313-9; Neuro Endocrinol Lett. 2008 Jun;29(3):287-91; Neuro Endocrinol Lett. 2008 Jun;29(3):287-91)

  Chronic pain

  Multiple Food Sensitivities

  Inflammatory Bowel Disease

  Chronic Yeast Overgrowth symptoms

  Brain fog


What causes Leaky Gut?

Leaky gut and its spectrum of conditions can be caused by different factors. The more factors that apply to you, the higher your risk is for leaky gut. At the same time, if you have chronic issues such as chronic depression, chronic pain or autoimmune disorders, eliminating those factors will help you manage and improve your condition and reduce flare ups.


Here are the factors contributing to leaky gut:












         Processed Foods

         Excess Sugar

         Fast foods


         Brain Trauma


         Physical, emotional,

chemical stressors

         Cortisol surges

Low hormone levels of:

         Thyroid hormones





         Intestinal inflammation

         Free radicals

         H. Pylori

         Bacterial overgrowth

         Yeast overgrowth

         Intestinal virus

         Parasitic infection






          Diet is a big factor causing leaky gut. The standard American diet including fast foods, a lot of bread and pasta, processed foods, and excess sugar is all that is needed. In our February newsletter, we talked extensively about how gluten sensitivity causes leaky gut. Also alcohol promotes intestinal bacterial growth and intestinal permeability (Gastroenterol. 2008 Jul;135(1):194-204.e3; Alcohol. 2008 Aug; 42(5):349-61. Epub 2008 May 27)


          Multiple studies show that decreased brain activity leads to intestinal permeability and intestinal inflammation. It is therefore important to get the brain as healthy as possible while treating the gut to curtail conditions caused by leaky gut. (J Trauma. 2010 May;68(5):1059-64; J Neurotrauma. 2009 Aug;26(8):1353-9; Basic Clin Pharmacol Toxicol. 2008 Sep;103(3):247-54. Epub 2008 Jul 8.)


          We all experience stress in our lives from physical, emotional or chemical stressors. To some degree we all suffer from Post Traumatic Stress Disorder (PTSD). Studies show that people with a high degree of stress in their lives are predisposed to intestinal inflammation. (Gastroenterology. 2008 Jul;135(1):163-172.e1. Epub 2008 Mar 22; Curr Mol Med. 2008 Jun;8(4):274-81)


          Low levels of testosterone in males, low levels of estrogen and progesterone in females and low levels of thyroid hormones diminish the ability to dampen intestinal inflammation and to support the regeneration of the intestinal lining. (Inflammopharmacology, 2008 Feb; 16(1):40-7; Equine Vet J. 1992; 24(1):37-40 ; Anz J Surg. 2002; 72(9): 672-5; J Physiol. 2009 Jul 1; 587(t 13):3317-28. Epub 2009 May 11)


          As much as leaky gut causes autoimmune disorders, autoimmunity also leads to leaky gut as it destroys intestinal tissues.


          If you are sensitive to intestinal infections such as H. Pylori, parasitic infections, bacterial and yeast overgrowth, or intestinal viruses, you are at high risk for developing leaky gut.


          And last but not least, medications such as corticosteroids, anti-acids, antibiotics and xenobiotics cause leaky gut.


For more information about how we can help you with your Leaky Gut and how it causes your chronic condition, call our office at 408-517-0706 or visit our website at www.jamiesonhealthcenter.com.


Foods to avoid:

          Sugars: including corn syrup, high fructose corn syrup, molasses, honey, chocolate, candy, etc.

          High glycemic fruits: watermelon, mango, pineapple, raisins and canned fruits

          Grains: including gluten, wheat, oats, rice, barley, buckwheat, soy, corn, wheat germ, spelt, amaranth, kamut, millet, quinoa, etc.

          Gluten containing compounds: including wheat, breads, pasta, processed salad dressings, ketchup, soy sauce, barbeque sauces, condiments, modified food starch, etc.

          Dairy: including milk, whey, eggs, cheeses, creams, and mayonnaise, margarine, etc.

          Soy: including soy milk, soy sauce, soy protein, etc.

          Alcohol: including beer, wine, sake, cognac, liqueurs, etc.

          Lectins: including nuts, beans, soy, potatoes, tomatoes, eggplant, pepper, peanut oil, soy oil, etc.


          All processed foods

         All canned foods


Foods to eat:

          Most vegetables (except tomatoes, potatoes and mushrooms): including asparagus, spinach, lettuce, broccoli, beets, cauliflower, carrots, celery, artichokes, garlic, onion, zucchini, squash, rhubarb, cucumbers, turnips, watercress, etc.

          Fermented foods: including sauerkraut, kimchi, pickled ginger, mixed pickle, coconut yogurt, kombucha tea, etc.

          Meats: including fish, chicken, beef, lamb, organ meats, etc.

          Low glycemic fruits: apricot, plum, apple, peach, pear, cherries, berries, etc.

          Coconut: including coconut oil, coconut butter, coconut milk, etc.

          Herbal teas

          Olives and olive oil

         Raw butter


This dietary program is not caloric (quantity of food), so you are allowed to eat whenever you are hungry. However you must only eat from the list of allowed foods.


How can Leaky Gut be treated?

Many people think: Ill just take glutamine to repair my intestines. Unfortunately, treating leaky gut is much more complex. Glutamine can help repair the intestinal lining, but it cant stop the vicious cycle of and will not cure leaky gut. Treating leaky gut means addressing each one of the factors contributing to it and thereby restoring the balance in your overall health.


  As a first step, a leaky gut blood panel provides an accurate assessment of your condition, but more importantly it creates a baseline from which to compare clinical outcomes. Having objective data not only identifies the cause of your symptoms, but it can help monitor if you are improving and encourage you in staying compliant with the treatments.


  If you are eating a standard American diet, drastic diet changes will be needed to curtail leaky gut. Read the adjacent paragraph on which foods to eat and which ones to avoid.


  Gluten sensitivity equals leaky gut. That means when you are gluten sensitive, you have a leaky gut. You need to cut all grains from your diet. Unfortunately, many patients replace those foods with gluten free options like gluten free bread, gluten free pasta, which are made from other grains and starches. Very often patients react to other grains in the same way they react to gluten. If you have difficulty giving up foods that contain gluten, a blood panel can accurately identify gluten sensitivity. Another blood panel can identify any cross-reactive foods that cause the same issues and therefore need to be avoided. To learn more about gluten sensitivity and cross-reactive foods, please read our February 2011 newsletter.


  We suggest an intestinal repair program to help repair and break the vicious cycle of leaky gut. This program may include:

o    probiotics and prebiotics to support intestinal immunity

o    dietary powders containing flavonoids, saponins, carotenoids, phytochemicals, and antioxidants to support tissue health, especially during intestinal inflammation or discomfort; glycoproteins to support mucosa membranes when irritated; extracts with high mucilage content to soothe and help intestinal health, as well as plant sterols and ferulic acid to help modulate the enteric nervous system with intestinal motility and the secretion of digestive enzymes.

o    supplements curtailing intestinal infections, bacteria, yeast and candida


  If you are suffering from autoimmune issues, we can help you manage and control them by:

o    Helping you develop a healthy balance of nitric oxide to support tissue healing, dampen tissue inflammation and destruction, and modulate autoimmune reactions

o    Helping you optimize your glutathione recycling system to prevent autoimmune flare ups and prevent intestinal destruction

o    Helping you maintain healthy levels of Vitamin D to support the integrity of the intestinal mucosal barrier.


  We can help you identify, eliminate and/or manage any physical, chemical and emotional stressors using an integrative approach with Applied Kinesiology, Neuro-Emotinal Technique and Nutritional Response Testing. Nutritional support can help you detoxify harmful chemicals.


  Chiropractic adjustments as well as Advanced Neurofeedback treatments help stimulate your brain. As mentioned above, there is a direct connection between the brain and the gut. As the brain gets less stimulation, it starts to degenerate and causes gut dysfunction, and vice versa. This is why seniors often struggle with digestive issues, e.g. constipation and heartburn: as their brains get older, start to degenerate or arent as challenged anymore, gut function decreases. Additional nutritional support can help you curtail brain inflammation and neurodegeneration.


For more information about how we can help you with your Leaky Gut and how it causes your chronic condition, call our office at 408-517-0706 or visit our website at www.jamiesonhealthcenter.com.



Samuel R. Jamieson, D.C.

Applied Kinesiology


Emotional Stress Relief

Total Body Modification

Advanced Neurofeedback


1175 Saratoga Ave, Ste 8

San Jose, CA 95129

Phone 408.517.0706

Email drjamieson@sbcglobal.net



Were on the Web!




Seminars weve taken.

Since I want to make a difference in your lives and that of your children, Im constantly trying to keep up with the latest developments in healing practices, clinical research and new discoveries in the area of integrative holistic medicine. To that end, I have attended the following seminars and conferences over the last several months:


          Understanding the complexity of gluten sensitivity

          Breaking the complex web of leaky gut

          The brain-gut axis

          Nutrition Response Testing

          NeuroIntegration therapy Level 1 and Level 2 training

          Autoimmune regulation

          Functional Endocrinology

          NeuroEndocrine-Immune Axis of Andropause

          Metabolic Biotransformation: an overview of detoxification and weight management

          Restoring Gastrointestinal Health

          Practical Blood Chemistry

          Functional Neurology for the Primary Care Provider

          Neurotransmitters and Brain

          The Thyroid-BrainImmuno Connection

          Restorative Endocrinology: Balancing Female Hormones in Menopausal Women

          Restorative Endocrinology: Balancing Hormones in Cycling Women

          The Impacts of Estrogen on the NeuroEndocrine-Immune Axis

          Restorative Endocrinology: Balancing Male Hormones

          Advanced Nutrition Therapeutics for Addictions and OCD


Some patients have asked about previous newsletters and they can be found on our website at http://www.jamiesonhealthcenter.com/archive.htm


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